One author is a consultant for a company that manufactures related equipment. The company had no role in the design of the study or the interpretation of the results.
Over the past decade, work on editorial: molecular mechanisms underlying single-cell transcriptomes in a mouse model has grown from a specialist concern into a field with its own methods, journals and communities. This editorial introduces the contributions in this issue and places them in a wider context.
Three themes run through the articles. First, the authors pay close attention to the quality of the underlying evidence and to the assumptions that connect it to the conclusions. Second, they take reproducibility seriously: data, code and protocols are shared wherever possible. Third, they are candid about the limits of their findings.
We are grateful to the reviewers, who gave generously of their time, and to the members of the editorial board for their advice. We also thank the editorial office for its careful work on every manuscript.
The journal will continue to publish work that is rigorous, clearly written and openly available. We welcome suggestions from readers and invite submissions in all areas within our scope.
The datasets generated and analyzed during the study are available from the corresponding author on reasonable request.
The protocol was reviewed and approved by the Research Ethics Board of the participating institution.